Role of Prophylactic Antibiotics in Preventing Pelvic Infection After Surgical Evacuation

• Status: Recruiting
• Trial end date: 2021-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

To determine the role of antibiotic prophylaxis in the surgical management of miscarriage.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Anti-Bacterial Agents

Criteria

Inclusion criteria:

• Maternal age :18-35 years

• Gestational age: up to 12 6/7 weeks of gestation (confirmed by a reliable date for the last menstrual period or /and 1st trimester ultrasound scan).

• Singleton miscarriage

• Type of miscarriage: Incomplete or Missed miscarriage

• Surgical evacuation will be done within 2 weeks of diagnosis of miscarriage .

Exclusion criteria:

• Maternal age: younger than 18 years

• Induced miscarriage of pregnancy

• Septic miscarriage

• Evidence of infection

• Morbid obesity (BMI≥40kg/m2)

• Allergy to prophylactic antibiotics (i.e., doxycycline or metronidazole)

• Antibiotics use within 7 days before randomization