Role of Prophylactic Postoperative Antibiotics in HoLEP

• Status: Not yet recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to investigate whether prescribing a 3-day course of antibiotics after Holmium laser enucleation of the prostate (HoLEP) reduces the risk of urinary tract infection. The findings of this trial will have a major impact on clinical practice to either justify the prescription of antibiotics after HoLEP or give urologists more confidence in not prescribing antibiotics prophylactically after HoLEP.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Baylor Research Institute
• Collaborator: Albert Einstein Healthcare Network
• Treatments: Cephalexin; Ciprofloxacin; Nitrofurantoin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

Criteria

Inclusion Criteria:

• Men > 40 years old with moderate to severe lower urinary tract symptoms due to benign prostatic hyperplasia (BPH).

• Patient with negative preoperative urine culture.

Exclusion Criteria:

• Patients with history of recurrent urinary tract infection or uro-sepsis.

• Patient with preoperative infections

• Patient with indwelling urethral catheter

• Patient doing continuous intermitted catheterization (CIC)