Role of Sildenafil Citrate in Patients With Unexplained Recurrent Miscarriages

• Status: Unknown status
• Trial end date: 2012-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether sildenafil citrate is effective in improving uterine artery blood flow and oxidative stress in patients with unexplained recurrent miscarriages

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Citric Acid; Sildenafil Citrate

Criteria

Inclusion Criteria:

• Age 18-35 years

• Three or more recurrent miscarriages before the 24th week of gestation with no apparent cause for their previous losses

• Three or more months have elapsed since the last abortion

• Postmenstrual period

• No other therapy allowed during our treatment course

Exclusion Criteria:

• Concomitant use of organic nitrites, or nitrates

• Severe hepatic, renal, or cardiovascular impairment

• History of stroke or myocardial infarction

• Patients with retinitis pigmentosa.