Role of Statin Therapy in Prevention of Anthracycline-Induced Cardiotoxicity

• Status: Recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study aims at evaluating the role of Atorvastatin in prevention of Anthracycline induced cardiotoxicity

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Atorvastatin

Criteria

Inclusion Criteria:

• Female patients diagnosed with histology proven breast cancer with an indication to primary systemic therapy or adjuvant regimens based on anthracyclines

Exclusion Criteria:

• Patients with impaired LV systolic function (EF below 50%)

• Patients with severe valvular heart disease

• Patients previously diagnosed with coronary artery disease

• Patients with baseline elevated liver enzymes

• Patients with prior chemotherapy or radiation therapy

• Pregnant females