Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
Status:
Recruiting
Trial end date:
2021-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to find out why patients with post-traumatic stress disorder
(PTSD) have an increased risk for heart disease and high blood pressure later in life. A
second purpose is to find out what causes PTSD patients to have high adrenaline levels during
stress. This study will also test if a medicine called losartan improves high adrenaline
levels in patients with PTSD and if a certain gene that has to do with high blood pressure
might be associated with high adrenaline levels.
Phase:
Phase 2
Details
Lead Sponsor:
Emory University
Collaborator:
American Heart Association
Treatments:
Angiotensin II Angiotensinogen Atenolol Losartan Nitroprusside Oxymetazoline Phenylephrine