Role of Topical Putrescine (Fibrostat) for Prevention of Hypertrophic Scars in Mammoplasty Patients
Status:
Completed
Trial end date:
2016-07-15
Target enrollment:
Participant gender:
Summary
Linked to previous Clinical Trial E92:069 in which biochemical effect of 1,4 diaminobutane
was studied in human scar harvested at revision surgery after a 12 week application.
Analytical data was collected in this phase of the work completed in 1999. This was then
followed by clinical correlation in a scar prevention model with topical application of 1,4
diaminobutane for 12 weeks and measuring duredness , as well photographic and POSAS score
data for quality of scar formation.