Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery

• Status: Recruiting
• Trial end date: 2024-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Vitamin C with its antioxidant role has many indications. The objective of this study is to demonstrate that taking vitamin C as a preventive significantly reduces the occurrence of complex regional pain syndrome (CRPS) type 1 in the aftermath of a scheduled surgery of the upper limb.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre Hospitalier Universitaire, Amiens
• Treatments: Ascorbic Acid; Vitamins

Criteria

Inclusion Criteria:

• patients over 18 yo

• patients undergoing major surgery of the upper limb

• patients able to give their consent to follow the protocol of treatment and monitoring.

Exclusion Criteria:

• children,

• patients under guardianship,

• pregnant or lactating women,

• patients with hemochromatosis,

• allergy or known hypersensitivity to one of the molecules of treatment,

• patients suffering or having already suffered from complex regional pain syndrome type 1 or type 2,

• patients unable due to personal or professional mobility, to conduct post-operative follow up,

• patients undergoing surgery with nerve suture with nerve graft, emergency surgery,

• patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency,

• patients with chronic kidney disease