Role of the Catechol-O-methyltransferase (COMT) in the Physiological Regulation of Vigilance
Status:
Completed
Trial end date:
2014-04-01
Target enrollment:
Participant gender:
Summary
In this study, pharmacologic effects of COMT inhibition during sleep deprivation in healthy
subjects in dependence of their Val158Met genotype of COMT are studied. Potential effects are
identified by measurement of vigilance and cognitive performance as well as EEG measurements
during wake and sleep.
- Trial with medicinal product