Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population

• Status: Recruiting
• Trial end date: 2022-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary aim of this study is to evaluate the pharmacokinetics of serum ropivacaine concentrations following erector spinae plane peripheral nerve blocks in the pediatric population.

Secondary outcomes will assess the efficacy of the block with perioperative morphine equivalent consumption and pain scores.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Baylor College of Medicine
• Treatments: Ropivacaine

Criteria

Inclusion Criteria:

• Age: 6 months - < 18 years old;

• Chest tubes or minimally invasive video assisted thoracic surgery;

• Surgery scheduled between 7AM and 5PM

• Weight greater than 4kg

Exclusion Criteria:

• Renal dysfunction;

• Liver dysfunction;

• Hypoalbuminemia;

• Allergy to local anesthetic;

• Spinal hardware or instrumentation;

• Scoliosis;

• Obesity defined as a BMI >95% percentile