Ropivacaine Use Intraincisionally Versus Intraperitoneally for Post-Laparoscopic Cholecystectomy Pain

• Status: Completed
• Trial end date: 2017-08-15
• Target enrollment: 0
• Participant gender: All

Summary

Pain still remains a limiting factor in early discharge of patients undergoing laparoscopic cholecystectomy. Almost all earlier studies done to compare the efficacy of local anaesthetics used intraperitoneally as compared to intraincisionally used equal amounts of drugs at the two locations, usually 10-20 ml. Using this large amount of drug in the small space of intraincisional location as compared to similar amount of drug in large intraperitoneal space created an inadvertent bias in favor of patients receiving the drug intraincisionally so such patients naturally experienced less pain. The investigators decided to standardize the drug used at these two locations as 1ml/cm and conduct a new study comparing the effects of drugs in relieving pain when used at these two locations.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Jawaharlal Nehru Medical College
• Treatments: Ropivacaine

Criteria

Inclusion Criteria:

• All patients in the age group of 15-80 years

• Patients conferring to Grade I or II of American Society of Anesthesiologists (ASA) physical status classification system only

• Patients undergoing elective Laparoscopic Cholecystectomy

• Patients having symptomatic cholelithiasis only

• Patients operated by a single surgeon were included.

Exclusion Criteria:

• Patients with known allergic reactions to local anesthetics

• Cases that were converted to open cholecystectomy

• Patients with major intra-operative complications

• Patients suffering from acute cholecystitis, empyema or malignancy of gall bladder, having history of chronic pain or those taking frequent analgesics or opioids pre-operatively

• Patients with peptic ulceration, bleeding disorders, impaired renal and/or hepatic function, and sensitivity to NSAIDs or opioids.

• Patients in whom gall bladder (GB) stones are found incidentally on ultrasonography (USG) (asymptomatic cholelithiasis)

• Patients suffering from severe chronic medical diseases and morbid obesity

• Patients unable to comprehend instructions or having communication problems were excluded from the study.