Type 1 Diabetes is the most common life-long disorder with onset in childhood. Patients need
insulin injections, blood sugar monitoring several times each day, and adhere to a strict
diet. Adequate control of blood glucose is essential to prevent long term kidney and eye
complications that result in kidney failure and blindness. Adolescence is a time when
diabetes is difficult to control, due in part to high growth hormone levels causing insulin
resistance ( a state where the body does not respond as strongly to insulin). This study will
test whether treatment with rosiglitazone (an oral medication used frequently in type 2
diabetes) will reduce the insulin resistance of adolescence and improve the control of type 1
diabetes during puberty.
Phase:
Phase 4
Details
Lead Sponsor:
The University of New South Wales
Collaborators:
National Health and Medical Research Council, Australia Novo Nordisk A/S Sydney Children's Hospitals Network Sydney Children's Network