S0429: Docetaxel, Cetuximab, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer
Status:
Terminated
Trial end date:
2012-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the
growth of tumor cells, either by killing the cells or by stopping them from dividing.
Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some find
tumor cells and kill them or carry tumor-killing substances to them. Others interfere with
the ability of tumor cells to grow and spread. Radiation therapy uses high-energy x-rays to
kill tumor cells. Giving docetaxel and cetuximab together with radiation therapy may kill
more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of docetaxel when
given together with cetuximab and radiation therapy in treating patients with stage III
non-small cell lung cancer.