Overview

SAHA + CHOP in Untreated T-cell Non-Hodgkin's Lymphoma

Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to find out how well the drug Zolinza (vorinostat) works in combination with the drug combination called CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) to treat patients with untreated T-cell Non-Hodgkin's Lymphoma (NHL). The safety of these drugs in combination and the best dose of vorinostat when given in combination with CHOP will also be studied.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
M.D. Anderson Cancer Center
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Cyclophosphamide
Doxorubicin
Liposomal doxorubicin
Prednisone
Vincristine
Vorinostat