SPECT/CT Bone Scan Quantification Surgery

• Status: Not yet recruiting
• Trial end date: 2025-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The hypothesis of our study is that SPECT/CT bone scan fixation quantified by SUVMAX on a CZT solid state camera preoperatively would identify good responders to lumbar arthrodesis surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Central Hospital, Nancy, France

Criteria

Inclusion Criteria:

• Persons with back pain for at least 3 months (presumed to be due to degenerative disc disease or spondylolisthesis).

• Persons who have received full information about the organisation of the research and have signed the informed consent and :

• Age ≥ 18 years, having read and understood the information document.

• Affiliated to a social security scheme.

• Lumbar arthrodesis involving a maximum of 2 floors.

• Standardized lumbar arthrodesis surgery performed by one of the three senior neurosurgeons of the neurosurgery department of the Nancy CHRU, using similar surgical techniques.

Exclusion Criteria:

• Low back pain of neuropathic origin. The Neuropathic Pain Scale 4 questionnaire is used to diagnose neuropathic pain (score is ≥ 4/10)

• History of lumbar spine surgery

• Presence of other pathologies responsible for lumbar pain (multistage discopathies, ankylosing spondylitis, spondylodiscitis, rheumatoid arthritis, vertebral compression, vertebral metastasis, narrow lumbar canal, scoliosis, spondylolisthesis by isthmic lysis)

• Pregnant women or women of childbearing age without suitable contraception or nursing mothers.

• Unstable medical condition and/or inability to remain immobile in supine position during recordings.

• Known allergy to any component of the radiopharmaceutical (TECHNESCAN HDP).

• Person referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code.

• Persons deprived of their liberty by a judicial or administrative decision, persons under psychiatric care by virtue of Articles L. 3212-1 and L. 3213-1.

• Persons of full age who are unable to express their opposition.