Statins are known to cause rare but serious side effects such as rhabdomyolysis (breakdown of
muscle tissue) but many patients stop taking statins due to less severe symptoms, such as
muscle pain or fatigue.
This study aims to determine whether symptoms occurring during statin use are caused by
statins. The trial will compare patient-reported side effects of statins (20mg atorvastatin)
vs. placebo.
Patients will be randomized to alternating treatment blocks of either statin or placebo split
into six two-month treatment periods. At the end of each period, patients will be asked to
self-report side effects using a website or mobile app.
Phase:
Phase 4
Details
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborator:
National Institute for Health Research, United Kingdom