STRETCH Study: Effect of Distensibility on Endothelial-Dependent Vasoreactivity in Patients With ISH
Status:
Completed
Trial end date:
2006-01-01
Target enrollment:
Participant gender:
Summary
Determine whether increasing arterial distensibility by decreasing advanced glycation
end-product (AGE) cross-link components of vascular stiffness improves (a)
endothelial-mediated vasoreactivity at rest, as assessed by flow-mediated vasodilation (FMD),
and (b) endothelial-mediated vasoreactivity after exercise, as assessed by pulse
perfusion-mediated vasodilation (PPMV).