SUbstition of PERioperative Albumin Deficiency Disorders

• Status: Completed
• Trial end date: 2021-04-21
• Target enrollment: 0
• Participant gender: All

Summary

Aim of this study is to reduce postoperative complications (assessed by POMS-Score and graded by Clavien-Dindo-Score) by substitution of perioperative hypoalbuminaemia in high-risk patients or patients undergoing high risk surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Technische Universität München

Criteria

Inclusion Criteria:

• age: 18 years or older

• written informed consent

• ASA state 3 and 4 OR

• elective high risk surgery (open aortic surgery, open leg revascularization, thrombectomy, oesophagectomy, pancreatic surgery, cystectomy, liver surgery, change of knee- or hip-prothesis, amputation)

Exclusion Criteria:

• emergency surgery

• severe liver cirrhosis (child pugh C)

• need for dialysis

• patients already included in SUPERADD

• patients with a legal representative

• contraindications for human albumin: hypersensitivity for human albumin or any substance included in the preparation

• pregnancy

• breastfeeding women

• ASA state 5

• BMI > 35 kg/m2