Overview

Safe Accelerated Venetoclax Escalation in CLL

Status:
Recruiting
Trial end date:
2030-06-02
Target enrollment:
Participant gender:
Summary
This research study is trying to determine which patients with newly diagnosed or relapsed/refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), as grouped by their risk for tumor lysis syndrome (TLS), are able to safely tolerate an accelerated, daily venetoclax dose ramp-up rather than the standard approved schedule (5-week dose ramp-up). The name of the study drug involved in this study is: - Venetoclax The following drugs may also be included in some participants treatment regimen: - Obinutuzumab - Rituximab
Phase:
Phase 1
Details
Lead Sponsor:
Dana-Farber Cancer Institute
Treatments:
Obinutuzumab
Rituximab
Venetoclax