Overview

Safety And Efficacy Of Azacitidine, and Lenalidomide In Higher Risk Myelodysplastic Syndrome

Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
To evaluate the overall response rate of the combination of 5-azacitidine + Lenalidomide in high risk MDS patients (INT-2 and High risk defined by IPSS), and patients with low and int-1 who are considered to be at high risk due to unfavorable additional factors. - To evaluate the safety of the combination of 5-azacitidine + Lenalidomide in high risk MDS patients. - To evaluate the hematological improvement rate. - To evaluate the cytogenetic response rate. - To evaluate the Progression free survival (PFS). - To assess Quality of life.
Phase:
Phase 2
Details
Lead Sponsor:
Tel-Aviv Sourasky Medical Center
Treatments:
Azacitidine
Lenalidomide
Thalidomide