Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia
Status:
Terminated
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to assess the safety and feasibility of HBOC-201 in increasing
adequate wound healing in patients with severe peripheral vascular disease who are undergoing
lower limb amputation.
The hypothesis is that HBOC-201 will pass through the partially occluded lesions in the
peripheral arteries in the lower extremity and promote the wound healing process by
delivering oxygen to the oxygen deprived tissues. This will reduce the incidence of lower
limb wound complications at 60 days post-surgery and may reduce the incidence of a second
amputation.