Overview

Safety, Pharmacokinetics and Pharmacodynamics of BPS804 in Osteogenesis Imperfecta

Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
This is a randomized, open label intra-patient dose escalation study to evaluate safety and tolerability, pharmacokinetics, and pharmacodynamics of BPS804 in adults with osteogenesis imperfecta (OI). Pharmacodynamic effect will be determined by serological biomarkers and radiologic assessments. In addition, tolerability and pharmacokinetics (PK) will be evaluated.
Phase:
Phase 2
Details
Lead Sponsor:
Novartis Pharmaceuticals
Ultragenyx Pharmaceutical Inc