Overview

Safety Study Of Cetuximab Plus Dasatinib (BMS-354825) in Treating Advanced Solid Malignancies

Status:
Completed
Trial end date:
2013-02-01
Target enrollment:
Participant gender:
Summary
This is an open-label, safety study of cetuximab and differing dose levels of dasatinib in adult patients with advanced solid malignancies. Cetuximab will be administered as an intravenous infusion weekly. Dasatinib will be taken orally, once a day, on a continuous schedule at differing dose levels. The primary objective of this study is to determine the toxicities and the maximum tolerated doses of dasatinib when combined with cetuximab for the treatment of advanced solid tumors.
Phase:
Phase 1
Details
Lead Sponsor:
University of Pittsburgh
Collaborator:
Bristol-Myers Squibb
Treatments:
Cetuximab
Dasatinib