Safety Study of Intracerebral Topotecan for Recurrent Brain Tumors
Status:
Unknown status
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
This study will evaluate the safety and efficacy of a chemotherapeutic drug (topotecan) as it
is given directly into brain tumors by a delivery technique called convection-enhanced
delivery. This drug has been used for different types of cancer, but in this study it will be
given by an experimental delivery technique designed to maximize the amount of drug delivered
to the brain tumor and minimize the side effects in other parts of the body.
This study will also evaluate advanced magnetic resonance (MR) imaging techniques.
The study will assess quality of life parameters throughout the follow-up period.