Safety Study of Intranasal Oxytocin in Frontotemporal Dementia
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Oxytocin is a hormone produced by the brain that appears to have important roles in social
cognition and emotion in humans. In a pilot study, the effects of a single dose of oxytocin
on measures of emotion recognition and behaviour in patients with Frontotemporal Dementia
were investigated. The results from the pilot study suggested that oxytocin may be associated
with a modest improvement in neuropsychiatric behaviours seen in patients with Frontotemporal
Dementia. To further examine the safety and tolerability of oxytocin in this disorder, the
present study will examine the safety and tolerability of three different doses of intranasal
oxytocin administered to patients with Frontotemporal Dementia twice daily for 1 week.
Phase:
Phase 1
Details
Lead Sponsor:
Lawson Health Research Institute
Collaborator:
Consortium of Canadian Centres for Clinical Cognitive Research