Overview Safety, Tolerability, PK, and Pharmacodynamics(PD) of IONIS APOCIII-LRx in Healthy Volunteers With Elevated Triglycerides Status: Completed Trial end date: 2018-04-30 Target enrollment: Participant gender: Summary The purpose is to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of IONIS APOC-III-LRx given to healthy volunteer subjects. Phase: Phase 1 Details Lead Sponsor: Ionis Pharmaceuticals, Inc.Collaborator: Akcea Therapeutics