Overview

Safety, Tolerability, and Effect of TMC207 and Efavirenz in Healthy Volunteers

Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
Common treatments for tuberculosis (TB) can interfere with certain antiretroviral (ARV) medications used to treat HIV. People whose immune systems are weakened by HIV infection are susceptible to TB, so it is important to find treatments for both that can be given in combination. This study will test the safety of combining a new medication for TB with an already approved HIV medication in healthy adults.
Phase:
Phase 1
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Treatments:
Bedaquiline
Diarylquinolines
Efavirenz