Overview Safety, Tolerability, and Pharmacokinetic Study of ISIS ApoC-III Rx in Hypertriglyceridemia Status: Completed Trial end date: 2014-01-01 Target enrollment: Participant gender: Summary The purpose of this study is to evaluate the dose/response pharmacodynamic effects of ISIS ApoC-III Rx vs. Placebo on fasting total apoC-III levels. Phase: Phase 2 Details Lead Sponsor: Ionis Pharmaceuticals, Inc.