Safety and Effectiveness of Immunotherapy With Autologous HIV-Specific CD8 Cells in HIV Infected Adults
Status:
Completed
Trial end date:
2005-04-01
Target enrollment:
Participant gender:
Summary
Effective, suppressive treatment for HIV infected patients can be a major challenge because
HIV progressively destroys their immune systems. CD8 cells isolated from a patient's blood
and grown in large numbers in the laboratory may increase a patient's immune system response
to HIV. The purpose of this study is to determine if CD8 cells will provide effective
antiviral activity against HIV when transplanted back in large numbers into HIV infected
patients.
Study hypothesis: There are specific cells in the immune system that recognize and can kill
HIV-infected cells.
Phase:
Phase 1
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)