Overview

Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation

Status:
Completed
Trial end date:
2014-08-21
Target enrollment:
Participant gender:
Summary
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control. The purpose of this study is to assess the safety and effectiveness of low molecular weight sulfated dextran (LMW-SD) on post-transplant islet function in people with type 1 diabetes who have responded to intensive insulin therapy.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborators:
Clinical Islet Transplantation Consortium
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Treatments:
Antilymphocyte Serum
Basiliximab
Calcium heparin
Cyclosporine
Cyclosporins
Dextrans
Etanercept
Everolimus
Heparin
Mycophenolate mofetil
Mycophenolic Acid
Sirolimus
Tacrolimus
Thymoglobulin