Safety and Effectiveness of tPA in Intra-abdominal Abscesses

• Status: Terminated
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine if instillation of tissue plasminogen activator into a percutaneously drained intra-abdominal abscess cavity results in faster resolution of the abscess compared to normal standard of care.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Health Network, Toronto
• Treatments: Plasminogen; Tissue Plasminogen Activator

Criteria

Inclusion Criteria:

• Intrabdominal abscess

Exclusion Criteria:

• Hypersensitivity to tPA

• Recent stroke

• Uncontrolled htn

• Recent major hemorrhage

• Pregnancy