Safety and Efficacy Comparison of Docetaxel and Ixabepilone in Non Metastatic Poor Prognosis Breast Cancer
Status:
Completed
Trial end date:
2020-09-03
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor
cells, either by killing the cells or by stopping them from dividing. Giving more than one
drug (combination chemotherapy) and giving them after surgery may kill any tumor cells
remaining after surgery. It is not yet known whether docetaxel is more effective than
ixabepilone when given after surgery and combination chemotherapy in treating breast cancer.
PURPOSE: This randomized phase III trial is studying giving combination chemotherapy followed
by docetaxel or ixabepilone to compare how well they work in treating patients who have
undergone surgery for nonmetastatic breast cancer.