Safety and Efficacy Study of Intravenous Lidocaine After Colorectal Surgery: LIDOREHAB

• Status: Completed
• Trial end date: 2007-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to check if lidocaine intravenous administration during surgery and 24 hours after surgery, associated with standardised management of the patient, helps to accelerate recovery and to improve the quality of recovery, after surgery for colic or rectal neoplasms.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assistance Publique - Hôpitaux de Paris
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Colorectal neoplasm

• Radical surgery

• Median incision

Exclusion Criteria:

• American Society of Anesthesiologists (ASA) score equal to or up to 3

• Unwilling or unable to use patient-controlled analgesia (PCA)

• Chronic consumption of opioids

• Chronic drug or alcohol abuse

• Chronic pain

• Unable to read or write text

• Inflammatory disease of intestinal tract

• Allergy to morphine

• Allergy to lidocaine

• Severe atrioventricular conduction dysfunction without stimulator

• Porphyry

• Uncontrolled epilepsy

• History of malign hyperthermia

• Severe cardiac failure

• Hepatic failure

• Myasthenia

• Treatment with beta blockers, antiarrhythmic calcium blockers, sultopride, nonselective monoamine oxidase inhibitor (MAOI)

• Locoregional anaesthesia planned

• Associated surgery concerning liver, pancreas, or gall bladder

• Laparoscopic surgery

• Severe psychiatric pathology

• Refusal of the patient