Safety and Efficacy Study of NVR 3-778 in Healthy Volunteers and Hepatitis B Patients
Status:
Completed
Trial end date:
2016-05-18
Target enrollment:
Participant gender:
Summary
This Phase 1 trial will assess the dose-related safety and PK profile of different doses of
NVR 3-778, first in healthy volunteer subjects (part I) and subsequently in patients with
chronic hepatitis B (part II). Additionally, in Part II, changes in patients' serum HBV DNA
levels and other virologic efficacy parameters will be assessed.