Safety and Efficacy of Addition of Hyaluronidase to Lidocaine and Bupivacaine in Scalp Nerves Block in Elective Craniotomy Operations, Comparative Study

• Status: Completed
• Trial end date: 2018-04-24
• Target enrollment: 0
• Participant gender: All

Summary

Safety and efficacy of addition of hyaluronidase to lidocaine and bupivacaine in scalp nerves block in elective craniotomy operations,Comparative study

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Collaborators: Badawy Mohammed Al-Kholy; Hatem Abdellatif Mohamed; Mohamed Mahmoud Mohamed; Mohamed, Ahmed A., M.D.; Tarek Ahmed Radwan
• Treatments: Anesthetics; Anesthetics, Local; Bupivacaine; Lidocaine

Criteria

Inclusion Criteria:

1. ASA Ι and II.

2. Both males and females, age (18-60) years.

3. Supine position.

4. Glasco coma scale more than 12.

5. Elective craniotomy operations.

Exclusion Criteria:

1. ASA ΙII or IV

2. History of allergy to the study drugs.

3. Surgery to remove pituitary tumours or affecting pituitary hormones.

4. Glasco coma scale less than 12.

5. The need for postoperative ventilation.