Overview

Safety and Efficacy of Bexxar Therapy in the Treatment of Relapsed/Residual B-Cell Lymphoma After Autologous Transplant

Status:
Completed
Trial end date:
2015-05-01
Target enrollment:
Participant gender:
Summary
Patients with B-cell lymphoma who relapse after autologous transplant tend to have a poor prognosis. Currently, there is no standard treatment for such patients. Bexxar is a radioactive antibody therapy that has shown a 60-80% response rate in non-transplanted patients with relapsed B-cell lymphoma. This study will test the safety and efficacy of Bexxar in the treatment of patients whose B-cell lymphoma has relapsed after an autologous transplant.
Phase:
Phase 1
Details
Lead Sponsor:
University of Pennsylvania
Collaborator:
GlaxoSmithKline
Treatments:
Iodine-131 anti-B1 antibody
Tositumomab I-131