Safety and Efficacy of Bilateral Superficial Cervical Plexus Block in Thyroidectomy

• Status: Completed
• Trial end date: 2010-07-01
• Target enrollment: 0
• Participant gender: All

Summary

With thyroid surgery being performed as an ambulatory procedure, most recent studies concerning post thyroidectomy analgesia are focused on regional techniques such as bilateral superficial cervical plexus block (BSCPB) and bilateral combined superficial and deep cervical plexus block. But, data regarding the efficacy of BSCPB are controversial. Hence the investigators compared the efficacy of BSCPB with 0.25% bupivacaine with or without clonidine in thyroidectomy, as preemptive analgesia.

The hypothesis was bupivacaine with the addition of clonidine would help in reducing postoperative pain and thereby reduce the need for postoperative analgesia.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Jawaharlal Institute of Postgraduate Medical Education & Research
• Treatments: Bupivacaine; Clonidine

Criteria

Inclusion Criteria:

• Consenting consecutive euthyroid patients undergoing elective thyroidectomy under general anesthesia, of either genders and more than 18 years of age, belonging to the ASA class I and II.

Exclusion Criteria:

• Patients unable to understand visual analog pain score (VAS) or unable to use patient controlled analgesia (PCA).

• Patients with malignancy requiring block dissection or with substernal goiters - Contraindications to superficial cervical plexus block like allergy to local anesthetics, bleeding diatheses and local infection or sepsis.

• Contraindications to morphine like bronchial asthma and hypothyroidism.

• Sensitivity to the anesthetic agent used or intolerance to the medications used in the study.

• Patients who received steroids or opioids or other analgesics recently.

• Patients with history of stridor.