Safety and Efficacy of Dinoprostone (Propess) in the Women With Premature Rupture of Membrane or Gestational Age <38

• Status: Completed
• Trial end date: 2019-04-04
• Target enrollment: 0
• Participant gender: Female

Summary

Dinoprostone(propess) is commonly used for induction of labor in the pregnant women who has intact membrane after 38weeks of gestational age. The investigators study safety and efficacy of dinoprostone in the pregnant women with premature rupture of membrane or GA<38weeks

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital

Criteria

Inclusion Criteria:

• Pregnant women who admitted for induction of labor

• Bishop score <= 6

Exclusion Criteria:

• Contraindication to induction of labor

• Active labor

• Vaginal bleeding, unknown origin

• Hypersensitive to Prostaglandin E

• History of asthma, glaucoma

• Infection (birth canal)

• Placental abruption

• Multiparity(>5)

• Pelvic inflammatory disease

• Heart, lung, kidney disease

• Multiple pregnancy

• Major anomaly

• Fetal distress before induction of labor