Safety and Efficacy of Long-Term Treatment With Atorvastatin in Patients With Primary Biliary Cirrhosis
Status:
Completed
Trial end date:
2007-11-01
Target enrollment:
Participant gender:
Summary
Primary biliary cirrhosis (PBC) is frequently associated with hypercholesterolemia and
possibly with an increased cardiovascular morbidity and mortality. Statins lower serum
cholesterol levels and may thus improve the cardiovascular risk in PBC patients. The aim of
our study therefore was to prospectively examine the efficacy of low-dose atorvastatin on
indicators of cardiovascular risk such as dyslipidemia and vascular function as well as
safety in patients with PBC.