Safety and Efficacy of Three Different Loading Doses of Clopidogrel, in Patients With Acute Myocardial Infarction

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to determine both safety and effectiveness of three different loading dose regimens of clopidogrel in patients with acute myocardial infarction undergoing primary angioplasty.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ospedale San Donato
• Treatments: Clopidogrel; Platelet Aggregation Inhibitors; Ticlopidine

Criteria

Inclusion Criteria:

• ST-elevation myocardial infarction:

• chest pain lasting more than 30 minutes

• not responsive to nitrates

• ST-segment elevation of more than 0.1 mV in two or more leads on the ECG, or new Left Bundle Branch Block

• With indication to primary PCI, presenting within 12 hour from symptoms onset

• Age > 18 years

• Planned PCI

• Informed Consent

Exclusion Criteria:

• bleeding diathesis

• allergy to study drugs

• pregnancy

• the performance of a rescue PCI after thrombolysis

• known existence of a disease resulting in a life expectancy of <6 months

• lack of informed consent