Safety and PK of Nikkomycin Z for Coccidioides Pneumonia Treatment
Status:
Terminated
Trial end date:
2009-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if nikkomycin Z is safe when administered at
different dose levels for 14 days. The study will also determine blood levels and urinary
excretion of nikkomycin Z in relation to dose administered. Patients with mild forms of
Valley Fever pneumonia will be eligible to participate and will be allocated to receive
treatment with nikkomycin Z (various doses) or a placebo. A secondary goal of this study is
to evaluate the effectiveness and dose response of nikkomycin Z in an exploratory analysis.