Overview

Safety and TDM of Continuous Infusion Vancomycin Through Continuous Renal Replacement Therapy Solution

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this investigation is to evaluate the safety of delivering continuous infusion (CI) vancomycin in pediatric CRRT by utilizing CI via by mixing the vancomycin into the CRRT solution(s). The secondary objectives are to describe the ability to achieve therapeutic vancomycin concentrations by utilizing this new delivery technique. Primary Objectives: To determine whether delivering continuous infusion vancomycin mixed into the CRRT solution can maintain therapeutic levels of drug in patients being treated for proven or suspected Gram-positive bacterial infections.
Phase:
Phase 1
Details
Lead Sponsor:
Drexel University
Collaborator:
The Center for Pediatric Pharmacotherapy, LLC
Treatments:
Pharmaceutical Solutions
Vancomycin