Overview

Safety and Tolerability Study of Phenylbutyrate in Huntington's Disease (PHEND-HD)

Status:
Completed
Trial end date:
2006-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the safety, tolerability and clinical impact of 15-grams daily of sodium phenylbutyrate (phenylbutyrate) in Huntington's disease and to lay the groundwork for possible subsequent trials designed to specifically address its ability to slow or halt the progression of the disease.
Phase:
Phase 2
Details
Lead Sponsor:
University of Rochester
Collaborators:
Columbia University
HP Therapeutics Foundation
Johns Hopkins University
Massachusetts General Hospital
University of Alabama at Birmingham
University of California, San Diego
University of Iowa
University of Kansas
Treatments:
4-phenylbutyric acid