Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access

• Status: Completed
• Trial end date: 2018-04-21
• Target enrollment: 0
• Participant gender: All

Summary

Hypertonic saline is used to treat elevated intracranial pressure. Intraosseous vascular access has been used to administer fluids and medications. This study combines these to administer 3% hypertonic saline via IO.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ohio State University

Criteria

Inclusion Criteria:

• NCCU patients in which osmotherapy with HTS is planned (standard of care

• Does not already have a CVC or PICC.

Exclusion Criteria:

• <18 years old

• Known pregnancy

• Long bone fracture in the targeted site

• Proximity to prosthetic joint

• Excessive tissue/absence of anatomical landmarks

• History of osteopetrosis

• Previous significant orthopedic procedure at site

• Prosthetic limb or joint

• IO catheter use in the past 48 hours of the target bone

• Infection at the area of insertion

• Hypersensitivity to lidocaine