Overview

Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients

Status:
Terminated
Trial end date:
2007-03-01
Target enrollment:
Participant gender:
Summary
Scleroderma, or systemic sclerosis (SSc), is a diffuse connective tissue disease characterized by changes in the skin, blood vessels, skeletal muscles, and internal organs. The purpose of this study is to determine the safety and value of self bone marrow transplants after chemotherapy in patients with severe SSc.
Phase:
Phase 1
Details
Lead Sponsor:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborators:
Amgen
Genzyme, a Sanofi Company
University of Pittsburgh
Treatments:
Cyclophosphamide
Fludarabine
Fludarabine phosphate
Thymoglobulin