Overview

Safety of BKM120 Monotherapy in Advanced Solid Tumor Patients

Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
This is a first-in-man, phase I clinical research study with BKM120, a potent and highly specific oral pan-class I phosphatidylinositol-3-kinase (PI3K) inhibitor. The study consists of a dose escalation part followed by a MTD expansion part. Once the MTD has been defined, the MTD expansion part will be opened for enrollment.
Phase:
Phase 1
Details
Lead Sponsor:
Novartis Pharmaceuticals