Overview

Safety of Dialysate Sodium Individualization in Hemodialysis Patients With Intradialytic Hypotension

Status:
Terminated
Trial end date:
2008-10-01
Target enrollment:
0
Participant gender:
All
Summary
Low blood pressure (hypotension) during dialysis afflicts approximately 25% of hemodialysis patients. In this pilot study, we will evaluate the safety and effects of individualizing the sodium concentration in the dialysate according to the patient's own plasma sodium levels. We hypothesize that patients will have less thirst and less weight gain during the intervention leading to easier fluid removal and less episodes of hypotension.
Phase:
Phase 1
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Yale University
Treatments:
Dialysis Solutions
Criteria
Inclusion Criteria:

- Hemodialysis patients with intradialytic hypotension

Exclusion Criteria:

- Atrial fibrillation

- Bilateral upper extremity arteriovenous access

- Average plasma sodium >139