Safety of Hydromorphone in Adult Patients Presenting to the Emergency Department With Acute Severe Pain

• Status: Completed
• Trial end date: 2006-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the safety and speed of onset of 2mg intravenous hydromorphone (Dilaudid) in patients weighing at least 150 lbs presenting to the emergency department with acute severe pain

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Montefiore Medical Center
• Treatments: Hydromorphone

Criteria

Inclusion Criteria:

1. Age greater than 21 years

2. Age less than 65 years of age

3. Pain with onset within 7 days

4. ED attending physician's judgment that patient's pain warrants use of morphine

5. Normal mental status

Exclusion Criteria:

1. Prior use of methadone

2. Use of other opioids or tramadol within past seven days

3. Prior adverse reaction to hydromorphone.

4. Chronic pain syndrome

5. Alcohol intoxication

6. SBP <90 mm Hg

7. Use of MAO inhibitors in past 30 days

8. C02 measurement greater than 46