The investigators are doing this research study to find out if using aspirin along with
antidepressant treatment can lessen symptoms of depression. This study also aims to find out
if some people improve more from taking aspirin than others. The investigators also want to
see if it is possible to predict which participants will do better based on a blood test.
Aspirin is approved by the U.S. Food and Drug Administration (FDA) as an over-the-counter
pain medication. But, aspirin is not approved by the FDA to make antidepressant treatment
better.
This research study will compare aspirin to placebo.