Overview

Sanaria™ PfSPZ Challenge Vaccine

Status:
Completed
Trial end date:
2013-04-01
Target enrollment:
Participant gender:
Summary
This study will randomize 30 healthy adult participants to one of three cohorts comprised of six groups of 5 individuals per group to simultaneously receive PfSPZ Challenge via the ID route. The goal will be to determine the optimal dose required to achieve 100% infectivity (ID100) of adult volunteers with P. falciparum malaria.
Phase:
Phase 1
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Treatments:
Chloroquine
Chloroquine diphosphate
Vaccines