Screening for Barrett's Esophagus in Otolaryngology Patients
Status:
Unknown status
Trial end date:
0000-00-00
Target enrollment:
Participant gender:
Summary
The purpose of this project is to develop an accurate method to identify patients that
suffer from acid reflux, but may not present with classic reflux symptoms (such as heart
burn). Additionally, it is the purpose of this project to utilize the Unsedated
Small-caliber Endoscopy (USE) to assess the prevalence of Barrett's esophagus in a
population of patients with laryngopharyngeal reflux (LPR) symptoms and to define normal
patterns of LPR. Laryngopharyngeal reflux (LPR) is when a small amount of stomach contents
and acid are pushed up through the esophagus and may affect the vocal cords and upper
respiratory tract.
It is suspected that patients with LPR symptoms may have a prevalence of Barrett's esophagus
similar to that found in a population with typical reflux symptoms. We propose to
systematically test this hypothesis using the USE.
This project is designed to improve the methods of identifying patients with a form of acid
reflux that is often undetected, and thus untreated. If this project is successful then more
patients with Barrett's esophagus will be identified; furthermore, screening and treatment
for this pre-cancerous condition will be improved.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)